Pofuna kuwunikira khungu, arbutin, monga chopangira choyera chachilengedwe, akuyambitsa kusintha kwakhungu. Izi yogwira yotengedwa masamba zimbalangondo zipatso wakhala nyenyezi yonyezimira m'munda wamakono chisamaliro khungu chifukwa cha makhalidwe ake wofatsa, kwambiri achire zotsatira, ndi applicability lonse.
1. Kujambula kwasayansi kwaAlpha Arbutin
Arbutin imachokera ku hydroquinone glucoside, yomwe imapezeka makamaka muzomera monga zipatso, mitengo ya mapeyala, ndi tirigu. Mapangidwe ake a maselo amapangidwa ndi magulu a shuga ndi hydroquinone, ndipo mawonekedwe apaderawa amawathandiza kuti azitha kuletsa pang'onopang'ono kupanga melanin. Pankhani yosamalira khungu, alpha arbutin amakondedwa kwambiri chifukwa cha kukhazikika kwake komanso ntchito zake.
Njira yoyera ya arbutin imawonetsedwa makamaka pakuletsa ntchito ya tyrosinase. Tyrosinase ndi puloteni yofunika kwambiri mu kaphatikizidwe ka melanin, ndipo arbutin imalepheretsa kutembenuka kwa dopa kukhala dopaquinone, motero kumachepetsa kupanga melanin. Poyerekeza ndi hydroquinone yachikhalidwe, arbutin imakhala ndi mphamvu yocheperako ndipo siyiyambitsa kuyabwa kapena zotsatira zoyipa pakhungu.
Panthawi ya metabolic pakhungu, arbutin imatha kutulutsa pang'onopang'ono hydroquinone, ndipo njira yowongolera iyi imatsimikizira kulimba ndi chitetezo cha kuyera kwake. Kafukufuku wasonyeza kuti mutatha kugwiritsa ntchito mankhwala osamalira khungu omwe ali ndi 2% arbutin kwa masabata 8, malo amtundu wa khungu amatha kuchepetsedwa ndi 30% -40%, ndipo sipadzakhala chodabwitsa.
2, Ubwino wosamalira khungu
Chofunikira kwambiri cha arbutin ndikuyera kwake koyera komanso kuwunikira kwamawanga. Zambiri zakuchipatala zikuwonetsa kuti pakatha milungu 12 yogwiritsa ntchito mosalekeza zinthu zosamalira khungu zomwe zili ndi arbutin, 89% ya ogwiritsa ntchito adanenanso kusintha kwakukulu pakhungu komanso kuchepa kwapakati ndi 45% m'dera la pigmentation. Kuyera kwake kumafanana ndi hydroquinone, koma ndikotetezeka komanso koyenera kugwiritsidwa ntchito kwanthawi yayitali.
Pankhani ya antioxidant katundu, arbutin amawonetsa mphamvu zowononga zaulere. Kuyesera kwawonetsa kuti antioxidant ntchito yake ndi nthawi 1.5 kuposa ya vitamini C, yomwe imatha kuletsa ma radicals aulere opangidwa ndi UV ndikuteteza maselo akhungu ku kuwonongeka kwa okosijeni. Pakadali pano, arbutin imakhalanso ndi anti-inflammatory properties, yomwe imatha kuchepetsa kufiira kwa khungu, kutupa, ndi kuyabwa.
Pazotchinga pakhungu, arbutin imatha kulimbikitsa kuchuluka kwa keratinocyte ndikuwonjezera ntchito yotchinga khungu. Kafukufuku wasonyeza kuti mutagwiritsa ntchito zinthu zosamalira khungu zomwe zili ndi arbutin kwa milungu inayi, kutaya kwamadzi kwa transcutaneous (TEWL) pakhungu kumachepa ndi 25% ndipo chinyezi chapakhungu chimawonjezeka ndi 30%.
3, Kugwiritsa Ntchito ndi Zoyembekeza Zamtsogolo
M'munda wa zodzoladzola, arbutin wakhala akugwiritsidwa ntchito kwambiri makamaka, zonona kumaso, chigoba cha nkhope ndi zinthu zina zosamalira khungu. Kugwirizana kwake ndi zosakaniza monga niacinamide ndi vitamini C kumapereka mwayi kwa opanga ma formula. Pakadali pano, kukula kwa msika wa zinthu zosamalira khungu zomwe zili ndi arbutin zapitilira madola 1 biliyoni aku US, ndikukula kwapachaka kupitilira 15%.
Pazamankhwala, arbutin yawonetsa mwayi wogwiritsa ntchito kwambiri. Kafukufuku wasonyeza kuti ili ndi zinthu zosiyanasiyana zachilengedwe monga antibacterial, anti-inflammatory, and anti-tumor properties, ndipo imakhala ndi zotsatira zochiritsira zochizira matenda a khungu monga melasma ndi post inflammatory pigmentation. Mankhwala angapo opangidwa ndi arbutin alowa mu gawo la mayeso azachipatala.
Pakuchulukirachulukira kwa ogula pazosakaniza zoyera komanso zoyera, chiyembekezo chamsika wa arbutin ndichambiri. Kutuluka kwa arbutin sikunangobweretsa zosinthika pakuyera ndi kusamalira khungu, komanso kwapereka chisankho chabwino kwa ogula amakono omwe amatsata chisamaliro chotetezeka komanso chothandiza pakhungu. Chopangira choyera ichi chachilengedwe komanso chovomerezeka mwasayansi chikulemba mutu watsopano wosamalira khungu.
Nthawi yotumiza: Feb-26-2025
