Pankhani ya sayansi ya zodzoladzola, DL panthenol ili ngati kiyi yaukadaulo yomwe imatsegula chitseko cha thanzi la khungu. Kalambulabwalo wa vitamini B5, wokhala ndi chinyezi chabwino kwambiri, kukonza, komanso anti-kutupa, wakhala chinthu chofunikira kwambiri pakupanga ma skincare. Nkhaniyi ifotokoza zinsinsi zasayansi, mtengo wogwiritsa ntchito, komanso chiyembekezo chamtsogolo cha DL panthenol.
1. Kujambula kwa sayansi kwaDL panthenol
DL panthenol ndi mtundu wa racemic wa panthenol, wokhala ndi dzina la mankhwala 2,4-dihydroxy-N - (3-hydroxypropyl) -3,3-dimethylbutanamide. Mapangidwe ake a molekyulu ali ndi gulu limodzi loyamba la mowa ndi magulu awiri achiwiri a mowa, omwe amamupatsa hydrophilicity ndi permeability.
Kutembenuka kwapakhungu ndiye chinsinsi cha mphamvu ya DL panthenol. Pambuyo polowa pakhungu, DL panthenol imasinthidwa mwachangu kukhala pantothenic acid (vitamini B5), yomwe imagwira nawo ntchito yopanga coenzyme A, potero imakhudza kagayidwe ka mafuta acid ndi kuchuluka kwa maselo. Kafukufuku wasonyeza kuti kutembenuka kwa DL panthenol mu epidermis kumatha kufika 85%.
Njira yayikulu yochitirapo kanthu imaphatikizapo kupititsa patsogolo ntchito zotchinga pakhungu, kulimbikitsa kuchuluka kwa ma cell a epithelial, ndikuletsa kuyankha kotupa. Deta yoyesera imasonyeza kuti mutatha kugwiritsa ntchito mankhwala omwe ali ndi 5% DL panthenol kwa masabata a 4, kutaya kwa madzi a transdermal pakhungu kumachepetsedwa ndi 40%, ndipo kukhulupirika kwa stratum corneum kumakhala bwino.
2. Multidimensional ntchito yaDL panthenol
Pankhani ya moisturizing, DL panthenol imapangitsa kuti hydration ya stratum corneum iwonjezere chinyezi. Mayesero azachipatala awonetsa kuti kugwiritsa ntchito moisturizer yokhala ndi DL panthenol kwa maola 8 kumawonjezera chinyezi pakhungu ndi 50%.
Pankhani yokonza, DL panthenol imatha kulimbikitsa kuchuluka kwa maselo a epidermal ndikufulumizitsa ntchito yotchinga. Kafukufuku wasonyeza kuti postoperative ntchito mankhwala okhala DL panthenol akhoza kufupikitsa machiritso mabala nthawi ndi 30%.
Kwa chisamaliro champhamvu cha minofu, DL panthenol's anti-inflammatory and soothing zotsatira ndizodziwika kwambiri. Mayesero asonyeza kuti DL panthenol ikhoza kulepheretsa kutulutsa zinthu zotupa monga IL-6 ndi TNF - α, kuchepetsa kufiira kwa khungu ndi kukwiya.
Posamalira tsitsi, DL panthenol imatha kulowa mu tsitsi ndikukonza keratin yowonongeka. Pambuyo pogwiritsira ntchito mankhwala osamalira tsitsi omwe ali ndi DL panthenol kwa masabata a 12, mphamvu yosweka tsitsi imakula ndi 35% ndipo glossiness imakula ndi 40%.
3, Chiyembekezo chamtsogolo cha DL panthenol
Tekinoloje zatsopano zopanga monga nanocarriers ndi liposomes zasintha kwambiri kukhazikika komanso kupezeka kwa bioavailabilityDL panthenol. Mwachitsanzo, nanoemulsions akhoza kuonjezera permeability pakhungu DL panthenol ndi 2 zina.
Kafukufuku wachipatala akupitiriza kuzama. Kafukufuku waposachedwa akuwonetsa kuti DL panthenol ili ndi phindu pa chithandizo chamankhwala adjuvant matenda akhungu monga atopic dermatitis ndi psoriasis. Mwachitsanzo, kugwiritsa ntchito DL panthenol munali formulations odwala atopic dermatitis akhoza kuchepetsa kuyabwa zambiri ndi 50%.
Chiyembekezo cha msika ndi chachikulu. Zikuyembekezeka kuti pofika chaka cha 2025, msika wapadziko lonse wa DL panthenol ufika madola 350 miliyoni aku US, ndikukula kwapachaka kupitilira 8%. Ndi kufunikira kowonjezereka kwa zosakaniza zofatsa kuchokera kwa ogula, malo ogwiritsira ntchito DL panthenol adzakulanso.
Kupezeka ndi kugwiritsa ntchito DL panthenol kwatsegula nyengo yatsopano yosamalira khungu. Kuchokera pakunyowa ndi kukonza mpaka kudana ndi kutupa ndi kutonthoza, kuchokera ku chisamaliro cha nkhope kupita ku chisamaliro cha thupi, chophatikizira ichi chamitundumitundu chikusintha momwe timaonera thanzi la khungu. M'tsogolomu, ndi kupita patsogolo kwa teknoloji yopangira mapangidwe komanso kuzama kwa kafukufuku wachipatala, DL panthenol mosakayikira idzabweretsa zatsopano komanso mwayi wosamalira khungu. Panjira yofunafuna kukongola ndi thanzi, DL panthenol idzapitirizabe kugwira ntchito yapadera komanso yofunika kwambiri, ndikulemba mutu watsopano mu sayansi ya khungu.
Nthawi yotumiza: Mar-18-2025
