Sodium hyaluronateamapezeka kwambiri mu nyama ndi anthu physiologically yogwira mankhwala, pakhungu la munthu, madzimadzi synovial, umbilical chingwe, amadzimadzi nthabwala, ndi ophthalmic vitreous thupi amafalitsidwa. Kulemera kwake kwa maselo ndi 500 000-730 000 Dalton. Yankho lake lili ndi viscoelasticity komanso mbiri yake. Ndi chithandizo cha opaleshoni ya ophthalmic. Imasunga kuya kwina kwa chipinda cham'mbuyo pambuyo pa jekeseni m'chipinda cham'mbuyo. Ndi yabwino ntchito. Amatetezanso maselo a corneal endothelial ndi minofu ya intraocular, amachepetsa zovuta zogwirira ntchito, komanso amalimbikitsa machiritso a bala.
Gwero la Sodium hyaluronate
Sodium hyaluronatendi macromolecule polysaccharide yotengedwa mu bovine vitreous thupi. Ili ndi mikhalidwe itatu: yoletsa kukalamba komanso kusunga mwatsopano ndikutengera sayansi yasayansi.
Sodium hyaluronate ndi chimodzi mwa zigawo za khungu la munthu, ndi ambiri anagawira asidi mucosa mu thupi, alipo masanjidwewo wa connective minofu, ndipo ali wabwino moisturizing kwenikweni.
Makhalidwe a Sodium hyaluronate
Sodium hyaluronate ili ndi mikhalidwe itatu: anti-kukalamba komanso kusunga mwatsopano ndi biotechnology. Sodium hyaluronate ndi chimodzi mwa zigawo zikuluzikulu za khungu la munthu ndipo kwambiri kufalitsidwa acidic mucose mu thupi la munthu. Imakhala mu matrix a minofu yolumikizana ndipo imakhala ndi mphamvu yabwino yonyowa.
Ubwino wa Sodium Hyaluronate
1. Kupititsa patsogolo Pharmacodynamics
Hyaluronic acidndiye chigawo chachikulu cha minofu yolumikizana monga human interstitium, vitreous body, ndi synovial fluid. Ili ndi mawonekedwe osunga madzi, kusunga malo owonjezera, kuwongolera kuthamanga kwa osmotic, mafuta, ndikulimbikitsa kukonza ma cell mu vivo. Monga chonyamulira cha mankhwala ophthalmic, imatha kutalikitsa nthawi yosunga mankhwala m'maso mwa kuwonjezera kukhuthala kwa madontho a diso, kuwongolera kupezeka kwa mankhwala, komanso kuchepetsa kukwiya kwamankhwala m'maso.
The adjuvant therapy akhoza kubayidwa mwachindunji mu articular cavity ngati mafuta ochizira nyamakazi, monga jekeseni wa SPIT.
2. Crease Resistance
Kuchuluka kwa chinyezi pakhungu kumagwirizana kwambiri ndi zomwe zili mu hyaluronic acid. Ndi kukula kwa msinkhu, zomwe zili mu hyaluronic acid pakhungu zimachepa, zomwe zimachepetsa ntchito yosunga madzi pakhungu ndikupanga makwinya. Sodium hyaluronate amadzimadzi yankho ali wamphamvu viscoelasticity ndi lubricity. Akagwiritsidwa ntchito pamwamba pa khungu, amatha kupanga filimu yotulutsa chinyezi kuti khungu likhale lonyowa komanso lowala. Molekyulu yaying'ono ya hyaluronic acid imatha kulowa mu dermis, kulimbikitsa microcirculation ya magazi, kuthandizira khungu kuyamwa michere, ndikuchita ntchito yodzikongoletsera komanso yolimbana ndi makwinya.
3. Moisturizing Mmene
The moisturizing zotsatira ndi mbali yofunika kwambiri yasodium hyaluronate mu zodzoladzola. Poyerekeza ndi zokometsera zina, chinyezi chachifupi cha chilengedwe chozungulira sichimakhudza kwambiri mphamvu yake yonyowa. Izi wapadera chikhalidwe ndinazolowera khungu mu nyengo zosiyanasiyana, osiyana chilengedwe chinyezi, monga youma yozizira ndi yonyowa chilimwe, ndi zofunika zodzoladzola moisturizing kwenikweni. Kusungidwa kwa chinyezi cha sodium hyaluronate kumagwirizana ndi kulemera kwake ndi kulemera kwake.
4. Zotsatira Zazakudya
Sodium hyaluronate ndi chilengedwe chachilengedwe pakhungu, ndipo exogenous sodium hyaluronate ndi chowonjezera kuti amkati sodium hyaluronate pakhungu. Sodium hyaluronate yokhala ndi khalidwe lochepa imatha kulowa mu epidermis ya khungu, kulimbikitsa kupereka kwa zakudya zapakhungu ndi kutulutsa zinyalala, motero kupewa kukalamba kwa khungu, ndikuchita nawo mu cosmetology ndi kukongola. Kusamalira khungu ndikofunikira kwambiri kuposa zodzoladzola zina ndipo kwakhala chikhumbo cha anthu amakono kuti asunge nkhope.
5. Kukonza ndi Kupewa Kuwonongeka Kwa Khungu
Khungu limatenthedwa kapena kuwotchedwa ndi kuwala kwa dzuwa, monga reddening, blackening, peeling, etc., makamaka ndi ultraviolet kuwala kwa dzuwa. Sodium hyaluronate ikhoza kulimbikitsa kusinthika kwa khungu lovulala mwa kulimbikitsa kuchulukana ndi kusiyanitsa kwa maselo a epidermal ndi kutaya ma radicals opanda okosijeni. Kugwiritsa ntchito musanagwiritse ntchito kumakhalanso ndi chitetezo. Kachitidwe kake kachitidwe kake ndi kosiyana ndi kuyamwa kwa ultraviolet komwe kumagwiritsidwa ntchito kwambiri poteteza dzuwa. Chifukwa chake, hyaluronic acid ndi ultraviolet absorbent mu sunscreen skincare mankhwala amakhala ndi synergistic effect, yomwe imatha kuchepetsa kufalikira kwa cheza cha ultraviolet ndikukonzanso kuwonongeka kwa khungu komwe kumachitika chifukwa cha kuwala kochepa kwa ultraviolet, motero kuchita mbali ziwiri zoteteza.
Kuphatikiza kwa sodium hyaluronate ndi EGF (epidermal growth factor) kumatha kufulumizitsa kusinthika kwa maselo a epidermal ndikupanga khungu kukhala lachifundo, losalala komanso lotanuka. Khungu likakhala ndi zopsereza pang'ono ndi zowotcha, kugwiritsa ntchito zodzoladzola zamadzi zomwe zili ndi sodium hyaluronate pamtunda zimatha kuchepetsa ululu ndikufulumizitsa kuchira kwa khungu lovulala.
6. Mafuta ndi Kupanga Mafilimu
Sodium hyaluronate ndi mtundu wa polima wokhala ndi mafuta amphamvu komanso kupanga mafilimu. Zogulitsa pakhungu zomwe zili ndi sodium hyaluronate zimakhala ndi mafuta owoneka bwino komanso kumva bwino m'manja zikagwiritsidwa ntchito. Akagwiritsidwa ntchito pakhungu, filimu imatha kupangidwa pamwamba pa khungu, zomwe zimapangitsa kuti khungu likhale losalala komanso lonyowa, ndikuteteza khungu. Zopangira tsitsi zomwe zimakhala ndi sodium hyaluronate zimatha kupanga filimu yosanjikiza pamwamba pa tsitsi, yomwe imatha kunyowetsa, kuthira mafuta, kuteteza tsitsi, kuthetsa magetsi osasunthika, ndikupangitsa tsitsi kukhala losavuta kupesa, lokongola, komanso lachilengedwe.
7. Kukhuthala
Sodium hyaluronate imakhala ndi kukhuthala kwakukulu mu njira yamadzi. Itha kukhala ndi gawo la thickening ndi kukhazikika mu zodzoladzola.
8. Zotsatira za Pharmacological za Sodium Hyaluronate
Physiological yogwira zinthu amapezeka kwambiri nyama ndi anthu ndipo amagawidwa mu khungu la munthu, synovial madzimadzi olowa m'malo olumikizirana mafupa, umbilical chingwe, amadzimadzi nthabwala, ndi vitreous thupi la maso. Kulemera kwa molekyulu ndi 500000-730000 Dalton. Yankho lake lili ndi viscoelasticity komanso kutsanzira. Ndi chithandizo cha opaleshoni ya ophthalmic. Imasunga kuya kwina kwa chipinda cham'mbuyo pambuyo pa jekeseni m'chipinda cham'mbuyo, chomwe chiri choyenera kugwira ntchito. Amatetezanso maselo a corneal endothelial ndi minofu ya intraocular, amachepetsa zovuta, komanso amalimbikitsa machiritso a bala.
Nthawi yotumiza: Aug-23-2023
