Ferulic Acid - zopangira zoyera

Ferulic acidndi mankhwala achilengedwe omwe amapezeka muzomera zosiyanasiyana monga Angelica sinensis, Ligusticum chuanxiong, horsetail ndi mankhwala achi China, ndipo adapeza chidwi chifukwa cha zopindulitsa zake. Amapezekanso mu mankhusu a mpunga, nyemba za pandan, chimanga cha tirigu ndi chimanga cha mpunga. Izi zofooka za acidic organic acid zimakhala ndi phenolic acid dongosolo ndipo zimakhala ngati tyrosinase inhibitor. Mukaphatikizidwa ndi ma antioxidants amphamvu monga resveratrol ndivitamini C, ferulic acid ili ndi maubwino angapo monga kuyera khungu, chitetezo cha antioxidant, kupewa kupsa ndi dzuwa, ndi zotsatira zotsutsana ndi zotupa.

Chimodzi mwazinthu zochititsa chidwi za ferulic acid ndi antioxidant katundu wake. Kapangidwe kake ka phenolic hydroxyl kumapangitsa kuti ikhale yogwira ntchito motsutsana ndi ma radicals aulere, kuphatikiza ma radicals a superoxide ndi ma hydroxyl radicals. Pogwira ma elekitironi awiri okha kuchokera ku ma free radicals, ferulic acid imakhazikika pa molekyulu ndikuletsa kusamutsa kwa ma elekitironi, kuteteza thupi ku kuwonongeka kwa okosijeni. Kuonjezera apo, asidi a ferulic ali ndi chiyanjano cholimba cha Fe2 +, chomwe chidzayambitsa redox ndi kuchepetsa Fe2 +, kuchita mbali yofunika kwambiri mu ntchito ya antioxidant. Chochititsa chidwi n'chakuti, mphamvu yake yochepetsera mankhwala a Fe3 + kuposa yavitamini C.

Kuphatikiza pa zabwino zake za antioxidant, ferulic acid imakhalanso ndi zoyera. Chigawocho sichimangolepheretsa ntchito ya melanocyte B16V komanso imalepheretsa ntchito ya tyrosinase, kupereka njira ziwiri zopezera khungu loyera. Yankho lomwe lili ndi 5 mmol/L ferulic acid linaletsa ntchito ya tyrosinase ndi 86% yochititsa chidwi. Ngakhale pamlingo wocheperako wa 0.5mmol/L, asidi a ferulic adawonetsabe kuletsa kwakukulu kwa pafupifupi 35% pakuchita kwa tyrosinase.

Kuphatikiza apo, ferulic acid imakhalanso ndi mphamvu zoteteza dzuwa. Amateteza khungu ku kuwala koopsa kwa dzuwa, kupereka chitetezo chowonjezera ku dzuwa. Izi zimapangitsa kukhala chinthu choyenera muzodzitetezera ku dzuwamankhwala ndi njira zina zosamalira khungu zomwe zimapangidwira kuchepetsa mavuto akhungu okhudzana ndi UV.

Pomaliza, ferulic acid yawonetsedwa kuti ili ndi anti-inflammatory properties. Kuchepetsa kutupa, kungathandize kuthetsa zinthu zapakhungu monga redness, kuyabwa, ndi kutupa. Chifukwa chake, kuwonjezera ferulic acid kuzinthu zosamalira khungu kumathandizira kuti khungu likhale ndi thanzi komanso thanzi.

Mwachidule, asidi a ferulic amapezeka mochuluka muzomera zosiyanasiyana ndi zachilengedwe ndipo ali ndi ubwino wambiri pakhungu. Kuchokera ku mphamvu zamphamvu za antioxidant mpaka kuyera, kuteteza dzuwa ndi anti-inflammatory properties, ferulic acid ndi chinthu chosunthika chomwe chingathe kupititsa patsogolo ntchito zosamalira khungu ndikulimbikitsa khungu lathanzi.