Panthenol ndi yochokera ku vitamini B5, yomwe imadziwikanso kuti retinol B5. Vitamini B5, yomwe imadziwikanso kuti pantothenic acid, imakhala ndi katundu wosakhazikika ndipo imakhudzidwa mosavuta ndi kutentha ndi kupanga, zomwe zimapangitsa kuchepa kwa bioavailability. Chifukwa chake, kalambulabwalo wake, panthenol, nthawi zambiri amagwiritsidwa ntchito popanga zodzikongoletsera.
Poyerekeza ndi vitamini B5 / pantothenic acid, panthenol imakhala ndi mphamvu yokhazikika yokhala ndi kulemera kwa maselo a 205 okha. Ikhoza kulowa bwino mu stratum corneum ndikusintha mofulumira kukhala vitamini B5, yomwe ndi gawo lofunika kwambiri la kagayidwe ka thupi ndi zofunika kwambiri zopangira. kwa kaphatikizidwe ka coenzyme A.CoenzymeA ndi chinthu chothandizira pamachitidwe osiyanasiyana a enzyme m'thupi. Amatenga nawo gawo mu kagayidwe kazinthu zama cell, kupereka mphamvu zogwirira ntchito zamoyo. Kuphatikiza apo, imathandizanso kagayidwe kazinthu zosiyanasiyana zofunika pakhungu, monga cholesterol, mafuta acids, ndi sphingolipids synthesis.
Kugwiritsa ntchito panthenol pakhungu kunayamba mu 1944 ndipo kuli ndi mbiri yazaka zopitilira 70. Amagwiritsidwa ntchito makamaka mu zodzoladzola pofuna kunyowetsa, kutsitsimula, ndi kukonza zolinga.
Udindo wofunikira kwambiri
Moisturizingndi kukonza zotchinga
Panthenol palokha imakhala ndi ntchito zoyamwa ndi kusungirako chinyezi, pomwe imalimbikitsa kaphatikizidwe ka lipid, kukulitsa kuchuluka kwa mamolekyu a lipid ndi ma microfilaments a keratin, kukonza malo olimba pakati pa keratinocytes, ndikuthandizira kuti khungu lizigwira ntchito bwino. Tiyenera kukumbukira kuti kuti panthenol ipititse patsogolo chotchinga, ndende iyenera kukhala 1% kapena kupitilira apo, apo ayi 0,5% imatha kukhala yonyowa.
Zotonthoza
Kutonthoza kwa panthenol makamaka kumachokera ku mbali ziwiri: ① chitetezo ku kuwonongeka kwa okosijeni kupsinjika ② kuchepetsa kuyankha kwa kutupa.
① Panthenol imatha kuchepetsa kupanga kwamtundu wa okosijeni wokhazikika m'maselo a khungu, ndikuwongolera njira yakhungu ya antioxidant, kuphatikiza kulimbikitsa ma cell akhungu kuti afotokoze zambiri za antioxidant factor - heme oxygenase-1 (HO-1), potero kumapangitsa kuti pantothenic acid pakhungu pakhale antioxidant. akhoza kuchepetsa kuyankha kotupa. Pambuyo polimbikitsa keratinocytes ndi capsaicin, kutulutsidwa kwa zinthu zotupa IL-6 ndi IL-8 kumawonjezeka kwambiri. Komabe, pambuyo pa chithandizo cha pantothenic acid, kutulutsa kwazinthu zotupa kumatha kuletsedwa, motero kumachepetsa kuyankha kwa kutupa ndikuchotsa kutupa.
Limbikitsanikukonza
Pamene ndende ya panthenol ili pakati pa 2% ndi 5%, ikhoza kulimbikitsa kusinthika kwa khungu laumunthu lowonongeka. Pambuyo pochiza chitsanzo cha kuvulala kwa laser ndi panthenol, mawu a Ki67, chizindikiro cha kuchuluka kwa keratinocyte, kuwonjezeka, kusonyeza kuti ma keratinocyte ambiri adalowa mu chikhalidwe chowonjezereka ndikulimbikitsa kusinthika kwa epidermal. Panthawiyi, mawu a filaggrin, chizindikiro chofunika kwambiri cha kusiyana kwa keratinocyte ndi ntchito yotchinga, nawonso awonjezeka, kusonyeza kupititsa patsogolo kukonzanso khungu. Kafukufuku watsopano mu 2019 adawonetsa kuti panthenol imalimbikitsa machiritso a bala mwachangu kuposa mafuta amchere komanso amathanso kukonza zipsera.
Nthawi yotumiza: Aug-30-2024
