Urolithin A, Kulimbitsa Mphamvu Zam'khungu, Kulimbikitsa Collagen, ndi Zizindikiro Zosakalamba

Urolithin A

Kufotokozera Kwachidule:

Urolithin A ndi metabolite yamphamvu ya postbiotic, yopangidwa pamene mabakiteriya a m'matumbo amathyola ellagitannins (omwe amapezeka mu makangaza, zipatso, ndi mtedza). Mu skincare, imakondweretsedwa chifukwa choyambitsamitophagy-njira ya "kuyeretsa" yam'manja yomwe imachotsa mitochondria yowonongeka. Izi zimathandizira kupanga mphamvu, kumalimbana ndi kupsinjika kwa okosijeni, komanso kumathandizira kukonzanso kwa minofu. Ndibwino kwa khungu lokhwima kapena lotopa, limapereka zotsatira zotsutsana ndi ukalamba pobwezeretsa nyonga ya khungu kuchokera mkati.

Dzina Lamalonda:Cosmate® UA

Dzina lazogulitsa:Urolithin A

Dzina la INCI:Urolithin A

Nambala ya CAS:Zithunzi za 1143-70-0

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Urolithin Andi metabolite yopangidwa ndi mabakiteriya am'matumbo ochokera ku ellagitannins - ma polyphenols omwe amapezeka mwachilengedwe mu makangaza, zipatso, ndi mtedza. Chodziŵika chifukwa cha mphamvu yake yapadera ya bioactivity, chophatikizika ichi chatulukira monga njira yopambana yopangira zodzikongoletsera, zomwe zimapereka njira yochirikizidwa ndi sayansi yokonzanso khungu.UrolithinA amagwira ntchito pama cell kuti athandizire thanzi la mitochondrial, "nyumba zamphamvu" zama cell akhungu, omwe ndi ofunikira kwambiri pakupanga mphamvu komanso kukonza minofu. Mwa kukhathamiritsa ntchito ya mitochondrial, imathandizira kutsitsimutsa khungu lotopa, lopanikizika, kuchepetsa kuoneka kwa kutopa ndikubwezeretsanso kuwala kwaunyamata. Kuthekera kwake kulimbikitsa kaphatikizidwe ka collagen ndi elastin kumalimbitsanso kamangidwe ka khungu, kuchepetsa mizere yosalala, makwinya, ndi kugwa.UrolithinA imakhala yokhazikika m'mapangidwe osiyanasiyana, kuchokera ku ma seramu opepuka mpaka mafuta olemera. Imaphatikizana mosasunthika ndi zinthu zina zogwira ntchito monga hyaluronic acid, vitamini C, ndi retinol, kupititsa patsogolo mphamvu zawo ndikusunga kugwirizana kwa khungu.

Ntchito Yofunikira ya Urolithin A:

Imakulitsa ntchito ya mitochondrial m'maselo akhungu kuti ipititse patsogolo kupanga mphamvu

Imalimbikitsa kaphatikizidwe wa collagen ndi elastin kuti khungu likhale lolimba

Amachepetsa kupsinjika kwa okosijeni ndikuletsa ma free radicals

Imathandizira ntchito yotchinga khungu komanso kusunga ma hydration

Imachepetsa zizindikiro za ukalamba (mizere yabwino, makwinya, kufooka).

Njira YochitiraUrolithin A:

Urolithin A imakhala ndi zotsatira zake kudzera m'njira zingapo:

Thandizo la Mitochondrial: Imayambitsa mitophagy-njira yachilengedwe yomwe maselo amachotsa mitochondria yowonongeka ndikusintha ndi zatsopano, zogwira ntchito. Kukonzanso uku kumathandizira kupanga mphamvu zama cell, kumapangitsa kuti khungu lizitha kukonzanso ndikukonzanso

Chitetezo cha Antioxidant: Monga antioxidant wamphamvu, imachotsa ma radicals aulere opangidwa ndi kuwonekera kwa UV komanso kupsinjika kwa chilengedwe, kuteteza kuwonongeka kwa okosijeni pama cell akhungu ndi DNA.

Kutsegula kwa Collagen: Imawongolera majini omwe amakhudzidwa ndi kupanga kolajeni ndi elastin (mwachitsanzo, COL1A1, ELN), kulimbitsa matrix a extracellular ndikuwongolera khungu.

Inflammation Modulation: Imachepetsa ma cytokines oyambitsa kutupa, kutonthoza khungu lokwiya komanso kumathandizira kuti khungu lizikhala lathanzi.

Ubwino ndi Ubwino wa Urolithin A:

Mphamvu Yochirikizidwa ndi Sayansi: Mothandizidwa ndi maphunziro a preclinical omwe akuwonetsa nyonga yapakhungu komanso kuchepetsa zolembera za ukalamba.

Chiyambi Chachilengedwe: Chochokera ku zomera zotchedwa ellagitannins, zokopa anthu ogula kukongola koyeretsa.

Kugwirizana Kosiyanasiyana: Imagwira ntchito ndi mitundu yosiyanasiyana (ma seramu, mafuta opaka, masks) ndikulumikizana ndi zinthu zina.

Zotsatira Zanthawi Yaitali: Zimalimbikitsa thanzi la khungu lokhalitsa pothana ndi ukalamba pamlingo wa ma cellular, osati mawonekedwe apansi.

Khungu: Zosakwiyitsa komanso zoyenera pakhungu lovutirapo zikagwiritsidwa ntchito pazovomerezeka

MFUNDO ZOFUNIKA KWAMBIRI

ZINTHU	SZOFUNIKA
Maonekedwe	Ufa wotuwa-woyera mpaka wotuwa
Chizindikiritso	HNMR imatsimikizira kupanga
Mtengo wa LCMS	LCMS imagwirizana ndi MW
Purity (HPLC)	≥98.0%
Madzi	≤0.5%
Chotsalira Choyaka	≤0.2%
Pb	≤0.5ppm
As	≤1.5ppm
Cd	≤0.5ppm
Hg	≤0.1ppm
E.Coli	Zoipa
Methanol	≤3000ppm
TBME	≤1000ppm
Toluene	≤890ppm
DMSO	≤5000ppm
Acetic Acid	≤5000ppm